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Science
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PROGRAMME INFO
Tuesday 21:00-21:30
Repeat Wednesday 16:30
DrÌýMark PorterÌýgives listeners the low-down on what the medical profession does and doesn't know. Each week an expert in the studio tacklesÌýa particular topic and there are reports from around the UK on the health of the nation - and the NHS.
Contact Case Notes
LISTEN AGAINListenÌý30 min
Listen toÌý6 March
PRESENTER
DR MARK PORTER
Dr Mark Porter
PROGRAMME DETAILS
TuesdayÌý6 MarchÌý2007
Birmingham Children's Hospital
Birmingham Children's Hospital

Full programme transcript >>

Leukaemia

For today’s programme Mark travels to Birmingham Children’s Hospital to find out about recent developments in the treatment of leukaemia.

Of the childhood forms, acute lymphoblastic leukaemia (ALL) is the most common type and typically strikes early in life, while the less common acute myeloid leukaemia (AML) tends to present in older children and teenagers.

The last forty years have seen a radical improvement in the outlook for children with leukaemia. In the 50s and 60s fewer than 1 in 20 children were still aliveÌýfive years after diagnosis. Today that figure is closer to 17 out 20 for ALL, and 13 out 20 for AML. Leukaemia is curable.

Mark talks to Paediatric Haematologist Sarah Lawson about Minimal Residual Disease (MRD) – a new technique that allows doctors to spot children in whom the disease is more likely to come back, allowing them to tailor treatment accordingly.
If a child’s disease is more resistant, they can be offered extra chemotherapy to reduce the chance of recurrence. ÌýIf MRD shows that a child has responded well then it may be possible to cut back on the amount of treatment they need, reducing the likelihood of unwanted side effects and complications.

Although the most common of all childhood cancers it’s actually quite rare before the age of 16 with nine out of ten cases occurring in adults. Caroline Swinburne meets Hazel who was diagnosed with AML in her early fifties.
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