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Germline cells

Germline cells are (sperm and ova) and the stem cells that divide to form gametes.

Germline cells can divide by mitosis to produce more germline cells to maintain the chromosome number. Diploid cells have 23 pairs of homologous chromosomes.

They can also divide by to produce gametes.

The nucleus of a germline stem cell undergoes two divisions, firstly separating homologous chromosomes and secondly separating chromatids. Haploid gametes contain 23 single chromosomes.

Two parents are needed in . During this process the nuclei of the male and female are fused in order to create a .

This process is known as fertilisation.

The gametes contain half the number of chromosomes (they are ). When the male and female gametes combine, they create the full complement of chromosomes (the zygote produced is ) in order to create a human embryo.

Gametes are formed by a type of cell division called .

The gametes in:

  • animals are sperm and eggs
  • flowering plants are pollen and eggs

Meiosis

In meiosis:

  1. copies of the genetic information are made
  2. the cell divides twice to form four gametes, each with a single set of chromosomes (haploid)
  3. all gametes are genetically different from each other, they show variation
A diagram illustrating the process of meiosis and how it creates gametes

The cells formed in meiosis are all genetically different. This is because the chromosomes - and genes - separate and are reshuffled during the process.

MitosisMeiosis
Produces genetically identical daughter cellsProduces genetically varied daughter cells
Daughter cells have a full set of chromosomes (diploid)Daughter cells have half a set of chromosomes (haploid)
2 daughter cells are produced4 daughter cells are produced
Occurs in all body cells except gamete forming cellsOnly occurs in gamete forming cells
MitosisProduces genetically identical daughter cells
MeiosisProduces genetically varied daughter cells
MitosisDaughter cells have a full set of chromosomes (diploid)
MeiosisDaughter cells have half a set of chromosomes (haploid)
Mitosis2 daughter cells are produced
Meiosis4 daughter cells are produced
MitosisOccurs in all body cells except gamete forming cells
MeiosisOnly occurs in gamete forming cells