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Anti-diuretic hormone (ADH)

The water content of the blood is controlled by a hormone called anti-diuretic hormone (ADH). Different amounts of ADH are released into the bloodstream by a gland in the brain according to the concentration of the .

The concentration of the blood can be altered by:

  • excess drinking (increases water content)
  • excess sweating (decreases water content)
  • consumption of salty foods (decreases water content)

These diagrams show what happens when there is either too little or too much water in the blood.

Too little water in blood. Hypothalmus detects water level. Pituitary gland releases ADH.  More water reabsorbed by kidneys. Less water lost in urine.  Blood water level returns to normal.
Too much water in blood. Hypothalmus detects water level.  Pituitary gland releases less ADH. Less water reabsorbed by kidneys. More water lost in urine.  Blood water level returns to normal.
PlasmaProblemADH releaseEffect of ADHEffect on urine
High concentrationToo little waterIncreasesMore water reabsorbed by nephronsMore concentrated
Low concentrationToo much waterDecreasesLess water reabsorbed by nephronsMore dilute
PlasmaHigh concentration
ProblemToo little water
ADH releaseIncreases
Effect of ADHMore water reabsorbed by nephrons
Effect on urineMore concentrated
PlasmaLow concentration
ProblemToo much water
ADH releaseDecreases
Effect of ADHLess water reabsorbed by nephrons
Effect on urineMore dilute

This type of control is an example of . It keeps the concentration of the blood plasma approximately constant.