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Australia spinner Nathan Lyon suffered a right calf injury during day two of the second Ashes Test at Lord's and will be assessed further after play.

Lyon pulled up when running to field a ball and had to be helped by the physio as he walked back to the dressing room.

Earlier in England's innings, the 35-year-old took his 496th Test wicket by dismissing opener Zak Crawley.

The off-spinner took eight wickets in Australia's victory in the first Test at Edgbaston last week.

"We're going to miss him for this game and could miss him for quite a while," said Australia batter Steve Smith.

"It didn't look good. It would be a big loss for us."

Lyon is playing his 100th consecutive Test, only the seventh player in history and first bowler to do so.

"He was really looking forward to taking part in and having a role in that," added Smith. "Fingers crossed he is OK."

After Lyon left the field, Australia took three England wickets for 34 runs to leave the home side 278-4 at the close, 138 runs behind.

"If he isn't OK it is a big miss for them," said England opener Ben Duckett. "I wish him the best and hope it's not too bad. You never want to see someone go down on the opposite side."

Off-spinner Todd Murphy, who made his debut in February and has played four Tests, is the only other spinner in Australia's squad.

Murphy, 22, returned figures of 7-124 in his first Test against India and took another seven in the rest of the series.