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Amid ongoing discussion of the developing situation in Ukraine, US President Joe Biden says an invasion by Russia 鈥渨ould be the largest invasion since World War II鈥� and that there would be 鈥渆normous consequences鈥� for Russia if an invasion were to take place.

Fears are growing over the fate of hundreds of children believed to be held by jihadist extremists inside a besieged prison in north-east Syria. We speak to Fionnuala N铆 Aol谩in, UN Special Rapporteur on the promotion and protection of human rights while countering terrorism.

And we hear from the South African billionaire who has just opened the first manufacturing plant in Africa to produce Covid-19 vaccines from start to finish.