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The United Nations makes an urgent call for aid for the people of Afghanistan, the collapse of the government and the withdrawal of Western support has left a million children at risk of severe malnourishment.

A world first after a genetically modified pigs heart is transplanted into a man's body in the US, we hear from a surgeon who was inside the operating theatre.

And will Geneva talks ease tensions over Russia's troop buildup on the Ukraine border? We'll hear from a leading member of the European Parliament.

Plus sport with Isaac live from Cameroon for the Africa Cup of Nations.