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Shares in AstraZeneca fell by 15% as a new cancer treatment failed to meet expectations. We hear from Jay Iyer of the Access to Medicines Foundation in Amsterdam about the financial pressures on pharmaceutical giants. Also in the programme, we ask whether Nigeria needs a new national airline, 14 years after the collapse of Nigeria Airways. Drinksmaker Diageo's chief executive, Ivan Menezes tells us why the firm recently bought George Clooney's tequila brand Casamigos for a billion dollars. We have a report from Lapland on the business opportunities brought about by the midnight sun. Plus as Forbes magazine unveils the world's highest paid comedians, we find out who is laughing all the way to the bank.

(Picture: An AstraZeneca sign. Picture credit: Getty Images.)