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Husband and wife Karen and Mark talk about Karen's breast cancer diagnosis and mastectomy.

Katy recently gave birth and talks about being a good mum with her mother, Susan.

Caroline and Jennifer reflect on the impact that acne has had on their lives.

A mother agonises over giving consent for her son's medical treatment.

Two friends celebrate the individual qualities of their Down's Syndrome children.

Husband and wife Tony and Vicky always look on the positive side of life.

Their marriage of seventeen years has been tested to the limit by his depression.

Hannah has a twin sister Ruth. She also has another sister Kate, who is severely disabled.

Carol and Rob remember their friend Ian who died of a brain tumour in August 2012

Beth asks dad Sean what he was thinking when he saw her for the first time.

Mark has Downs Syndrome. His older brother Neil has always wanted to protect him.

Alison and Caitlin recall the difficult relationship they both had with Alison's mum.

It's now five years since Edward's kidney transplant. He & his mum reflect on the surgery.

Lee and Shelley discuss the anguish of burying their son two days before his 2nd birthday.

When the rock in a relationship dies what anchors a mum bringing up three daughters?

Who listens to a therapist? Elaine is a psychotherapist and Renata works in counselling...

Colin has M.E. and thinks he's to blame for his mother's illness.

Natalie talks to her mum Mary about hiding her self-harm from the family.

Helen had polio at 15 months old. Her daughter is discovering its effect on her mum's life

Gill is fearless for herself, but is fearful for Paul. Can he face a future without her?

Helen tells her mum that life is harder as an adult without her childhood disfigurement.

Best friends Agnes and Nancy say dementia has focused them on life rather than death.

Pam and Jonathan are mother and son. Here they talk about Jonathan’s time in the army.

Mother and son Noreen and Rory talk about a death which shook their family last year.