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Does it matter where our stuff is made? Manufacturing's great shift west is well underway, but why is it happening and what does it mean for the global economy? Tanya Beckett hears from top trade expert, Michael McAdoo of Boston Consulting Group about how the pandemic and strained ties between the US and China are driving the changes. And the head of international policy at America's biggest business group, John Murphy of the US Chamber of Commerce, explains why the Inflation Reduction Act and the decisions his members make about where to manufacture goods have global consequences. Plus Aaron Heslehurst explores the challenges of Brexit, global competition and making a major acquisition in the middle of a pandemic with the CEO of the London Stock Exchange Group, David Schwimmer.