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For the last 15 years mum of two, Gemma, has battled cluster headaches up to ten times a day. Experts often refer to them to as 'suicide headaches' because the pain is said to be the worst that any human can experience. This crippling condition is destroying family life and particularly taking its toll on husband, Simon. It's a major challenge for Dr Chatterjee. So far, no one has been able to help Gemma overcome her condition and the family are desperate for a cure.

Gary Farmer lost his leg in a car crash when he was five years old, but he's overcome his disability and achieved success as a Paralympic ice hockey player. However, a lifetime on crutches and a punishing exercise regime has severely damaged his shoulders and he will soon be confined to a wheelchair. It's up to Dr Chattergee to come up with a solution to keep him on his feet and able to compete.