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Revealing the rich and controversial past of sugar, alcohol, tobacco and opium, Hollywood actor Brian Cox embarks on a thought-provoking journey to uncover how the commercial exploitation of these products hooked the rest of the world on an appetite for a good time.

In this first episode, Brian wants to find out why (like millions of other Brits), he is a diabetic. Starting in Barbados, from which sugar cane fuelled a consumer revolution, Brian discovers how the British acquired a 'sweet tooth' and why today, this has led to epidemic levels of diabetes, obesity and even addiction to sugar.