Katheryn of Berain (1534/5-1591) married four times and through her numerous children and grandchildren became known as the Mother of Wales. She was the daughter of Tudur ap Robert Vychan of Berain, Denbighshire. It is likely this portrait was painted in the northern Netherlands by the Friesian artist van Cronenburgh. The skull is symbolic of mortality and often occurs in sixteenth-century portraits.
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